Nothing was going to make week two look all that appealing following the Best Opening Week Everâ„¢ but that’s all behind us now as college football provides us with some beauties this time around. There are numerous high-profile games on the docket this week and that includes two of Notre Dame’s opponents facing each other.

Let’s go!

Enemy Watch

South Florida (-14) at Syracuse

Boston College (+6) at Virginia Tech

Old Dominion (+21.5) at NC State

Navy (-6) at Tulane

Army (OFF) at UTEP

Duke (+6.5) at Northwestern

USC (+8.5) at #7 Stanford

The Cardinal have been waiting for two weeks to try and send the creaky USC ship into full sinking mode. If you recall, the Tree had a bye last week. This is the 3rd meeting in just over a year with the Trojans having lost the last 2 and 6 out of the last 8 games in the series. It’s a bit of an interesting situation–do we hope Stanford becomes our “biggest” game of the year at the expense of a possible dud in L.A. to end the year? If USC loses this game we might see Clay Helton on track to be fired before the year is over.

Syracuse got Lamar Jackson’d last week and I’ve been on the USF is sneaky good bandwagon for a while. I’m not sure I’d be willing to bet a couple touchdowns with the way the Orange can move the ball.

Duke and Northwestern was somewhat of an important game last year. Now, both are coming off a pair of the ugliest losses on the season. The Blue Devils especially, who looked like a possible trap game-type of matchup, are looking a lot more like a Duke team pre-David Cutcliffe. Perhaps the magic has worn off with the old man.

Raised Eyebrow Game

Pitt (+6.5) at Oklahoma State

I noticed this game in the summer and thought it was such a weird and unusual matchup with some intrigue. Now, we have Okie Light ready to be about as pissed off as a team can be following their stolen victory by officials against Central Michigan. Yet, Pittsburgh is seemingly trending in a real positive direction and this could be a big win for Narduzzi & Co.

Double Raised Eyebrow Game

#6 Houston (-7.5) at Cincinnati

Greg Ward is playing which is good because Houston’s lone loss last year (Diaco!) came without Ward and this had the potential to get a little shootout-y on the road against a decent team.

National Spotlight

#2 Florida State (-2.5) at #10 Louisville

#25 Miami (-3.5) at Appalachian State

#22 Oregon (+3) at Nebraska

#1 Alabama (-10) at #19 Ole Miss

#3 Ohio State (-2) at #14 Oklahoma

UCLA (-3) at BYU

Derwin James is out 5 to 7 weeks for Florida State and that opens the door even further for Lamar Jackson to put on a wonderful show and Heisman moment. He’ll also face Clemson in a couple more weeks. We should get some clarity on Jackson’s ceiling by then. Anyone buying the Cardinal as a legit National Title contender? Remember, they also face Houston later in the season.

This weekend begins a pretty rough 6 to 7 week stretch for Miami which will define their season. They looked okay last week and haven’t played a team worth a damn quite yet. Going on the road to a really good App State has plenty of upset potential.

Ole Miss has Alabama right where they want them–lurking in the bushes with a loss already and not that menacing. Of course, that’s why Nick Saban was such a ball of fury last week after whooping a decent Western Kentucky squad. He knows the Tide have to be completely on their game to revenge 2 straight losses to the Rebels.

Speaking of laying in the weeds there hasn’t been much talk about Ohio State yet this year. Especially compared to last year when it was OMG DRAMA all day for an attempted title defense. In my preseason predictions I felt like if Oklahoma lost to Houston (check) they would come back and win this one at home against Ohio State. I guess I’ll still stick to that but I don’t expect the Buckeyes to lose the rest of the year.